Doctor profile · Federal record

Dr. William Karnes, MD

Gastroenterology Physician (CMS: Internal Medicine) · Orange, CA

  • NPI 1881652998
  • Accepts Medicare
  • MIPS 91.2 / 100 · 2023
  • 44 yrs in practice
  • Male
  • Solo practice
  • No sanctions

Practice & contact

NPPES Updated May 11, 2026
Primary practice
101 the City Dr S Bldg 22C
Orange, CA 928683201
(888) 717-4463
fax (714) 456-8858

Credentials & registration

NPPES · NUCC
NPI registered
May 2006 — 20 yrs on file
Profile last updated
September 8, 2014
Year of graduation
1982 — 44 yrs since
Specialty taxonomy
207RG0100X — NUCC code
State license (1)
California #G57458

Federal sanctions & exclusions

OIG LEIE Updated May 11, 2026

No sanctions, exclusions or revocations on file

Checked against OIG LEIE on NPI 1881652998. Last verified May 11, 2026.

Medicare procedures · 2023

Top services delivered

CMS Provider Utilization
Total services
962
Distinct HCPCS
10
Medicare allowed
$146,476
HCPCS Description Services Patients Avg allowed
45385 Removal of polyps or growths of large bowel using an endoscope with mechanical snare 150 149 $267
99214 Established patient office or other outpatient visit, 30-39 minutes 140 124 $140
43239 Biopsy of esophagus, stomach, and/or upper small bowel using a flexible endoscope 137 135 $109
99204 New patient office or other outpatient visit, 45-59 minutes 96 96 $182
45380 Biopsy of large bowel using a flexible endoscope 84 84 $107
43235 Diagnostic exam of esophagus, stomach, and/or upper small bowel using a flexible endoscope 48 47 $105
99442 Telephone medical discussion with physician, 11-20 minutes 46 44 $98
G0105 Colorectal cancer screening; colonoscopy on individual at high risk 40 40 $194
91110 Imaging of digestive tract done from the inside of the digestive tract 39 38 $121
99443 Telephone medical discussion with physician, 21-30 minutes 34 33 $136

In context: peer comparison

Among 16 peers in Orange Gastroenterology Physician, average services per provider: 65. This provider delivers 15× the peer median.

Medicare Part D · 2023

Top prescriptions

CMS Part D Prescriber
Total claims
1,104
Patients
519
Total drug cost
$177,047
Drug Type Claims Patients Total cost
Peg 3350-Electrolyte (Sodium Chloride/Nahco3/Kcl/Peg) Brand 295 280 $6,576
Omeprazole Generic 252 103 $7,932
Famotidine Generic 132 43 $6,804
Pantoprazole Sodium Generic 112 37 $2,060
Linzess (Linaclotide) Brand 62 28 $88,146
Sucralfate Generic 43 13 $16,921
Gavilyte-C (Peg3350/Sod Sulf,Bicarb,Cl/Kcl) Brand 31 0 $683
Ondansetron Odt (Ondansetron) Brand 31 15 $1,590
Dicyclomine Hcl Generic 27 0 $1,554
Lubiprostone Generic 23 0 $5,412

Frequently asked questions

Auto-generated from federal data
What is Dr. William Karnes's medical specialty?
Dr. William Karnes practices Gastroenterology Physician in Orange, CA.
Where does Dr. William Karnes practice?
Dr. William Karnes practices at 101 the City Dr S Bldg 22C, Orange, CA 928683201. Office phone: 8887174463.
What is Dr. William Karnes's NPI?
Dr. William Karnes's National Provider Identifier (NPI) is 1881652998, issued by NPPES.
Does Dr. William Karnes accept Medicare assignment?
Yes. Dr. William Karnes accepts Medicare assignment, meaning Medicare-allowed amounts are accepted as full payment for covered services.
What procedures does Dr. William Karnes commonly perform?
Top Medicare-reported procedures in 2023: Removal of polyps or growths of large bowel using an endoscope with mechanical snare (HCPCS 45385); Established patient office or other outpatient visit (HCPCS 99214); Biopsy of esophagus, stomach, and/or upper small bowel using a flexible endoscope (HCPCS 43239). Source: CMS Medicare Physician & Other Practitioners file.