Doctor profile · Federal record

Dr. Ryan Knake, PA-C

Physician Assistant · Cape Coral, FL

  • NPI 1063805745
  • Accepts Medicare
  • 11 yrs in practice
  • Male
  • Group practice
  • No sanctions

Practice & contact

Operates at 2 locations .

NPPES Updated May 11, 2026
Primary practice
2721 del Prado Blvd S Ste 230B
Cape Coral, FL 339045993
(239) 458-1196
fax (239) 458-1345
Additional location
7341 Gladiolus Dr
Fort Myers, FL 339085101
(239) 489-3420
Mailing address
2160 Colonial Blvd
Fort Myers, FL 339071410

Credentials & registration

NPPES · NUCC
NPI registered
March 2015 — 11 yrs on file
Profile last updated
December 7, 2017
Year of graduation
2015 — 11 yrs since
Specialty taxonomy
363A00000X — NUCC code
State license (1)
Florida #PA9108558

Federal sanctions & exclusions

OIG LEIE Updated May 11, 2026

No sanctions, exclusions or revocations on file

Checked against OIG LEIE on NPI 1063805745. Last verified May 11, 2026.

Medicare procedures · 2023

Top services delivered

CMS Provider Utilization
Total services
1,426
Distinct HCPCS
4
Medicare allowed
$89,188
HCPCS Description Services Patients Avg allowed
99232 Subsequent hospital care with moderate levelof medical decision making, if using time, at least 35 minutes 876 73 $69
99231 Subsequent hospital care with straightforward or low level of medical decision making, per day, if using time, at least 25 minutes 478 45 $44
99222 Initial hospital care with straightforward or low-level medical decision making, if using time, at least 55 minutes 58 58 $114
99221 Initial hospital care with straightforward or low level of medical decision making, per day, if using time, at least 40 minutes 14 14 $74

In context: peer comparison

Among 12 peers in this city , average services per provider: 181. This provider delivers 7.9× the peer median.

Open Payments

Industry payments received

CMS Open Payments
All-time total
$97
Transactions
4
Manufacturers
4
Payer (manufacturer) Industry Txns Amount
PFIZER INC. 1 $31.16
Novocure Inc. 1 $28.99
Myriad Genetic Laboratories, Inc. 1 $23.54
Janssen Biotech, Inc. 1 $13.58

By nature of payment

Food and Beverage
$97

Medicare Part D · 2023

Top prescriptions

CMS Part D Prescriber
Total claims
288
Patients
138
Total drug cost
$41,429
Drug Type Claims Patients Total cost
Tamsulosin Hcl Generic 72 32 $763
Bicalutamide Generic 40 21 $2,032
Dexamethasone Generic 29 21 $659
Tramadol Hcl Generic 26 19 $109
Ssd (Silver Sulfadiazine) Brand 22 19 $618
Lidocaine Hcl Viscous (Lidocaine Hcl) Brand 20 15 $350
Prednisone Generic 19 0 $82
Abiraterone Acetate Generic 18 0 $36,260
Oxycodone Hcl Generic 16 11 $142
Fluconazole Generic 15 0 $193

Frequently asked questions

Auto-generated from federal data
What is Dr. Ryan Knake's medical specialty?
Dr. Ryan Knake practices Physician Assistant in Cape Coral, FL.
Where does Dr. Ryan Knake practice?
Dr. Ryan Knake practices at 2721 del Prado Blvd S Ste 230B, Cape Coral, FL 339045993. Office phone: 2394581196.
What is Dr. Ryan Knake's NPI?
Dr. Ryan Knake's National Provider Identifier (NPI) is 1063805745, issued by NPPES.
Does Dr. Ryan Knake accept Medicare assignment?
Yes. Dr. Ryan Knake accepts Medicare assignment, meaning Medicare-allowed amounts are accepted as full payment for covered services.
What procedures does Dr. Ryan Knake commonly perform?
Top Medicare-reported procedures in 2023: Subsequent hospital care with moderate levelof medical decision making (HCPCS 99232); Subsequent hospital care with straightforward or low level of medical decision making (HCPCS 99231); Initial hospital care with straightforward or low-level medical decision making (HCPCS 99222). Source: CMS Medicare Physician & Other Practitioners file.