Doctor profile · Federal record

Dr. Melissa Lyle, MD

Advanced Heart Failure and Transplant Cardiology Physician (CMS: Advanced Heart Failure and Transplant Cardiology) · Cardiovascular Disease Physician · Cardiovascular Disease Physician · Jacksonville, FL

  • NPI 1427386697
  • Accepts Medicare
  • MIPS 76.2 / 100 · 2023
  • 13 yrs in practice
  • Licensed in 2 states
  • Female
  • Group practice
  • No sanctions

Practice & contact

NPPES Updated May 11, 2026
Primary practice
4500 San Pablo RD S
Jacksonville, FL 322241865
(904) 953-2000

Credentials & registration

NPPES · NUCC
NPI registered
November 2009 — 17 yrs on file
Profile last updated
September 15, 2022
Year of graduation
2013 — 13 yrs since
Specialty taxonomy
207RA0001X — NUCC code
State licenses (2)
Florida #ME145735 · Minnesota #58103

Federal sanctions & exclusions

OIG LEIE Updated May 11, 2026

No sanctions, exclusions or revocations on file

Checked against OIG LEIE on NPI 1427386697. Last verified May 11, 2026.

Medicare procedures · 2023

Top services delivered

CMS Provider Utilization
Total services
751
Distinct HCPCS
10
Medicare allowed
$89,926
HCPCS Description Services Patients Avg allowed
99233 Subsequent hospital care with moderate levelof medical decision making, if using time, at least 50 minutes 297 54 $120
93750 Evaluation of lower heart chamber assist device 98 17 $41
99214 Established patient office or other outpatient visit, 30-39 minutes 83 61 $126
99213 Established patient office or other outpatient visit, 20-29 minutes 71 53 $89
99291 Critical care, first 30-74 minutes 66 14 $218
76932 Ultrasonic guidance for biopsy of heart muscle 49 31 $37
93505 Biopsy of heart muscle 48 30 $232
99205 New patient office or other outpatient visit, 60-74 minutes 15 15 $221
93451 Insertion of tube in right heart chambers for measurement 13 12 $134
99214 Established patient office or other outpatient visit, 30-39 minutes 11 11 $91

In context: peer comparison

Among 3 peers in Jacksonville Advanced Heart Failure and Transplant Cardiology Physician, average services per provider: 75. This provider delivers 10× the peer median.

Medicare Part D · 2023

Top prescriptions

CMS Part D Prescriber
Total claims
471
Patients
54
Total drug cost
$1,281,049
Drug Type Claims Patients Total cost
Spironolactone Generic 54 24 $615
Vyndamax (Tafamidis) Brand 44 0 $1,166,264
Farxiga (Dapagliflozin Propanediol) Brand 42 0 $33,877
Metoprolol Succinate Generic 40 18 $1,418
Entresto (Sacubitril/Valsartan) Brand 37 0 $44,759
Bumetanide Generic 35 12 $1,731
Sulfamethoxazole-Trimethoprim (Sulfamethoxazole/Trimethoprim) Brand 32 0 $239
Pravastatin Sodium Generic 31 0 $278
Pantoprazole Sodium Generic 30 0 $175
Eliquis (Apixaban) Brand 27 0 $30,728

Hospital affiliations

CMS Hospital Compare

Frequently asked questions

Auto-generated from federal data
What is Dr. Melissa Lyle's medical specialty?
Dr. Melissa Lyle practices Advanced Heart Failure and Transplant Cardiology Physician in Jacksonville, FL.
Where does Dr. Melissa Lyle practice?
Dr. Melissa Lyle practices at 4500 San Pablo RD S, Jacksonville, FL 322241865. Office phone: 9049532000.
What is Dr. Melissa Lyle's NPI?
Dr. Melissa Lyle's National Provider Identifier (NPI) is 1427386697, issued by NPPES.
Does Dr. Melissa Lyle accept Medicare assignment?
Yes. Dr. Melissa Lyle accepts Medicare assignment, meaning Medicare-allowed amounts are accepted as full payment for covered services.
What procedures does Dr. Melissa Lyle commonly perform?
Top Medicare-reported procedures in 2023: Subsequent hospital care with moderate levelof medical decision making (HCPCS 99233); Evaluation of lower heart chamber assist device (HCPCS 93750); Established patient office or other outpatient visit (HCPCS 99214). Source: CMS Medicare Physician & Other Practitioners file.