Doctor profile · Federal record

Dr. Karam Al-Issa, M.D.

Hematology & Oncology Physician (CMS: Internal Medicine) · Internal Medicine Physician · Student in an Organized Health Care Education/Training Program · Indianapolis, IN

  • NPI 1720468259
  • Accepts Medicare
  • MIPS 28.7 / 100 · 2023
  • 13 yrs in practice
  • Male
  • Solo practice
  • No sanctions

Practice & contact

Operates at 3 locations .

NPPES Updated May 11, 2026
Primary practice
535 Barnhill Dr
Indianapolis, IN 462025116
(317) 948-6942
Additional location
9500 Euclid Ave
Cleveland, OH 441950001
(216) 444-2200
Additional location
11725 Illinois St Ste 565
Carmel, IN 460323011
(317) 688-5250
Mailing address
250 N Shadeland Ave
Indianapolis, IN 462194959

Credentials & registration

NPPES · NUCC
NPI registered
May 2015 — 11 yrs on file
Profile last updated
September 27, 2021
Year of graduation
2013 — 13 yrs since
Specialty taxonomy
207RH0003X — NUCC code
State license (1)
Indiana #01080058A

Federal sanctions & exclusions

OIG LEIE Updated May 11, 2026

No sanctions, exclusions or revocations on file

Checked against OIG LEIE on NPI 1720468259. Last verified May 11, 2026.

Medicare procedures · 2023

Top services delivered

CMS Provider Utilization
Total services
1,048
Distinct HCPCS
10
Medicare allowed
$117,398
HCPCS Description Services Patients Avg allowed
99214 Established patient office or other outpatient visit, 30-39 minutes 213 100 $91
99215 Established patient office or other outpatient visit, 40-54 minutes 211 35 $131
99233 Subsequent hospital care with moderate levelof medical decision making, if using time, at least 50 minutes 190 70 $111
99232 Subsequent hospital care with moderate levelof medical decision making, if using time, at least 35 minutes 116 51 $74
99215 Established patient office or other outpatient visit, 40-54 minutes 88 19 $134
99214 Established patient office or other outpatient visit, 30-39 minutes 84 42 $91
99223 Initial hospital care with moderate level of medical decision making, if using time, at least 75 minutes 66 64 $163
99204 New patient office or other outpatient visit, 45-59 minutes 53 53 $124
99204 New patient office or other outpatient visit, 45-59 minutes 15 15 $124
99205 New patient office or other outpatient visit, 60-74 minutes 12 12 $156

In context: peer comparison

Among 25 peers in this city , average services per provider: 125. This provider delivers 8.4× the peer median.

Open Payments

Industry payments received

CMS Open Payments
All-time total
$17,749
Transactions
80
Manufacturers
15
Payer (manufacturer) Industry Txns Amount
PFIZER INC. 22 $13,656.99
GENZYME CORPORATION 4 $2,436.78
Merck Sharp & Dohme LLC 8 $163.88
SOBI, INC 5 $154.01
E.R. Squibb & Sons, L.L.C. 6 $151.26
AstraZeneca Pharmaceuticals LP 7 $137.64
Astellas Pharma US Inc 5 $88.40
Adaptive Biotechnologies Corporation 4 $80.90
Takeda Pharmaceuticals U.S.A., Inc. 3 $70.24
Janssen Biotech, Inc. 3 $66.96
ARRAY BIOPHARMA INC 4 $63.15
Mirati Therapeutics, Inc. 2 $63.00
ABBVIE INC. 3 $58.23
Gilead Sciences, Inc. 2 $51.73
Pharmacosmos Therapeutics Inc. 2 $39.24

By nature of payment

Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program
$15,536
Food and Beverage
$2,048
Education
$100
Travel and Lodging
$65

Medicare Part D · 2023

Top prescriptions

CMS Part D Prescriber
Total claims
380
Patients
71
Total drug cost
$750,610
Drug Type Claims Patients Total cost
Eliquis (Apixaban) Brand 93 20 $77,026
Anastrozole Generic 40 14 $1,387
Allopurinol Generic 34 0 $253
Oxycodone Hcl Generic 28 17 $449
Prochlorperazine Maleate Generic 27 20 $340
Hydroxyurea Generic 20 0 $717
Dexamethasone Generic 19 0 $250
Kisqali (Ribociclib Succinate) Brand 18 0 $301,411
Revlimid (Lenalidomide) Brand 18 0 $331,879
Abiraterone Acetate Generic 17 0 $36,129

Frequently asked questions

Auto-generated from federal data
What is Dr. Karam Al-Issa's medical specialty?
Dr. Karam Al-Issa practices Hematology & Oncology Physician in Indianapolis, IN.
Where does Dr. Karam Al-Issa practice?
Dr. Karam Al-Issa practices at 535 Barnhill Dr, Indianapolis, IN 462025116. Office phone: 3179486942.
What is Dr. Karam Al-Issa's NPI?
Dr. Karam Al-Issa's National Provider Identifier (NPI) is 1720468259, issued by NPPES.
Does Dr. Karam Al-Issa accept Medicare assignment?
Yes. Dr. Karam Al-Issa accepts Medicare assignment, meaning Medicare-allowed amounts are accepted as full payment for covered services.
What procedures does Dr. Karam Al-Issa commonly perform?
Top Medicare-reported procedures in 2023: Established patient office or other outpatient visit (HCPCS 99214); Established patient office or other outpatient visit (HCPCS 99215); Subsequent hospital care with moderate levelof medical decision making (HCPCS 99233). Source: CMS Medicare Physician & Other Practitioners file.