Doctor profile · Federal record

Dr. Mary Lee Villanueva, MD

Hematology & Oncology Physician (CMS: Medical Oncology) · Yankton, SD

  • NPI 1699857821
  • Accepts Medicare
  • 25 yrs in practice
  • Female
  • Group practice
  • No sanctions

Practice & contact

NPPES Updated May 11, 2026
Primary practice
1104 W 8Th St
Yankton, SD 570783306
(605) 665-7841
fax (605) 665-0546

Credentials & registration

NPPES · NUCC
NPI registered
October 2006 — 20 yrs on file
Profile last updated
July 3, 2020
Year of graduation
2001 — 25 yrs since
Specialty taxonomy
207RH0003X — NUCC code
State license (1)
South Dakota #6096
Medicaid
SD #6631890

Federal sanctions & exclusions

OIG LEIE Updated May 11, 2026

No sanctions, exclusions or revocations on file

Checked against OIG LEIE on NPI 1699857821. Last verified May 11, 2026.

Medicare procedures · 2023

Top services delivered

CMS Provider Utilization
Total services
35,578
Distinct HCPCS
10
Medicare allowed
$993,597
HCPCS Description Services Patients Avg allowed
J9271 Injection, pembrolizumab, 1 mg 10,800 13 $53
Q9967 Low osmolar contrast material, 300-399 mg/ml iodine concentration, per ml 8,800 64 $0
J0897 Injection, denosumab, 1 mg 4,500 16 $23
J2469 Injection, palonosetron hcl, 25 mcg 2,120 39 $1
J1100 Injection, dexamethasone sodium phosphate, 1 mg 1,816 33 $0
J2405 Injection, ondansetron hydrochloride, per 1 mg 696 11 $0
J7050 Infusion, normal saline solution, 250 cc 619 49 $1
80053 Blood test, comprehensive group of blood chemicals 557 256 $10
85025 Complete blood cell count (red cells, white blood cell, platelets), automated test and automated differential white blood cell count 497 242 $8
Q5108 Injection, pegfilgrastim-jmdb (fulphila), biosimilar, 0.5 mg 474 11 $120

In context: peer comparison

Among 1 peers in Yankton Hematology & Oncology Physician, average services per provider: 646. This provider delivers 55× the peer median.

Open Payments

Industry payments received

CMS Open Payments
All-time total
$78
Transactions
3
Manufacturers
2
Payer (manufacturer) Industry Txns Amount
Lilly USA, LLC 2 $50.37
Genentech USA, INC. 1 $28.03

By nature of payment

Food and Beverage
$78

Medicare Part D · 2023

Top prescriptions

CMS Part D Prescriber
Total claims
777
Patients
150
Total drug cost
$59,079
Drug Type Claims Patients Total cost
Anastrozole Generic 215 42 $4,537
Letrozole Generic 147 31 $2,167
Omeprazole Generic 57 12 $507
Potassium Chloride Generic 51 13 $1,904
Ondansetron Hcl Generic 50 23 $478
Eliquis (Apixaban) Brand 48 0 $26,804
Prochlorperazine Maleate Generic 31 15 $221
Imatinib Mesylate Generic 29 0 $17,983
Exemestane Generic 27 0 $3,188
Levothyroxine Sodium Generic 26 0 $204

Hospital affiliations

CMS Hospital Compare

Frequently asked questions

Auto-generated from federal data
What is Dr. Mary Lee Villanueva's medical specialty?
Dr. Mary Lee Villanueva practices Hematology & Oncology Physician in Yankton, SD.
Where does Dr. Mary Lee Villanueva practice?
Dr. Mary Lee Villanueva practices at 1104 W 8Th St, Yankton, SD 570783306. Office phone: 6056657841.
What is Dr. Mary Lee Villanueva's NPI?
Dr. Mary Lee Villanueva's National Provider Identifier (NPI) is 1699857821, issued by NPPES.
Does Dr. Mary Lee Villanueva accept Medicare assignment?
Yes. Dr. Mary Lee Villanueva accepts Medicare assignment, meaning Medicare-allowed amounts are accepted as full payment for covered services.
What procedures does Dr. Mary Lee Villanueva commonly perform?
Top Medicare-reported procedures in 2023: Injection, pembrolizumab, 1 mg (HCPCS J9271); Low osmolar contrast material, 300-399 mg/ml iodine concentration, per ml (HCPCS Q9967); Injection, denosumab, 1 mg (HCPCS J0897). Source: CMS Medicare Physician & Other Practitioners file.