Doctor profile · Federal record

Dr. John Isaac, M.D.

Interventional Cardiology Physician (CMS: Cardiovascular Disease (Cardiology)) · Cardiovascular Disease Physician · Houston, TX

  • NPI 1295799005
  • Accepts Medicare
  • MIPS 69.1 / 100 · 2023
  • 32 yrs in practice
  • Male
  • Group practice
  • No sanctions

Practice & contact

NPPES Updated May 11, 2026
Primary practice
6560 Fannin St, Ste 620
Houston, TX 770302761
(713) 791-1978
fax (713) 791-1870

Credentials & registration

NPPES · NUCC
NPI registered
April 2006 — 20 yrs on file
Profile last updated
October 25, 2016
Year of graduation
1994 — 32 yrs since
Specialty taxonomy
207RI0011X — NUCC code
State license (1)
Texas #K4090
Medicaid
TX #151665001

Federal sanctions & exclusions

OIG LEIE Updated May 11, 2026

No sanctions, exclusions or revocations on file

Checked against OIG LEIE on NPI 1295799005. Last verified May 11, 2026.

Medicare procedures · 2023

Top services delivered

CMS Provider Utilization
Total services
10,572
Distinct HCPCS
10
Medicare allowed
$2,509,095
HCPCS Description Services Patients Avg allowed
99214 Established patient office or other outpatient visit, 30-39 minutes 2,306 1,068 $131
J2785 Injection, regadenoson, 0.1 mg 1,860 465 $54
93306 Ultrasound of heart with color-depicted blood flow, rate, direction and valve function 731 692 $202
93298 Evaluation of cardiac rhythm monitor system, remote up to 30 days 710 91 $27
G2066 Interrogation device evaluation(s), (remote) up to 30 days; implantable cardiovascular physiologic monitor system, implantable loop recorder system, or subcutaneous cardiac rhythm monitor system, remote data acquisition(s), receipt of transmissions and tec 709 90 $38
93880 Ultrasound of both sides of head and neck blood flow 608 606 $197
93015 Exercise or drug-induced heart stress test with electrocardiogram (ecg) with supervision and review by physician 551 549 $70
93000 Routine electrocardiogram (ecg) using at least 12 leads with interpretation and report 429 359 $15
A9555 Rubidium rb-82, diagnostic, per study dose, up to 60 millicuries 402 398 $799
78431 Nuclear medicine studies of blood flow in heart muscle at rest and with stress with concurrent ct scan 398 398 $2,475

In context: peer comparison

Among 42 peers in this city , average services per provider: 116. This provider delivers 91× the peer median.

Open Payments

Industry payments received

CMS Open Payments
All-time total
$199,532
Transactions
392
Manufacturers
15
Payer (manufacturer) Industry Txns Amount
Esperion Therapeutics, Inc. 54 $50,448.57
Kiniksa Pharmaceuticals International, plc 56 $48,404.89
Amgen Inc. 77 $37,192.35
Regeneron Healthcare Solutions, Inc. 13 $14,744.48
Lilly USA, LLC 11 $14,187.72
Boehringer Ingelheim Pharmaceuticals, Inc. 24 $12,646.64
Boston Scientific Corporation 33 $9,973.86
E.R. Squibb & Sons, L.L.C. 24 $7,272.32
Abbott Laboratories 29 $1,870.42
Novartis Pharmaceuticals Corporation 17 $440.26
Novo Nordisk Inc 17 $383.63
PFIZER INC. 14 $353.79
AstraZeneca Pharmaceuticals LP 9 $350.96
Merck Sharp & Dohme LLC 10 $230.59
Actelion Pharmaceuticals US, Inc. 4 $208.48

By nature of payment

Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program
$161,084
Travel and Lodging
$27,182
Food and Beverage
$10,667
Consulting Fee
$600

Medicare Part D · 2023

Top prescriptions

CMS Part D Prescriber
Total claims
11,009
Patients
3,091
Total drug cost
$2,526,448
Drug Type Claims Patients Total cost
Ezetimibe Generic 1,663 538 $80,411
Rosuvastatin Calcium Generic 1,532 465 $28,292
Atorvastatin Calcium Generic 1,415 419 $20,915
Metoprolol Succinate Generic 969 290 $20,009
Repatha Sureclick (Evolocumab) Brand 920 140 $695,498
Amlodipine Besylate Generic 804 245 $9,272
Eliquis (Apixaban) Brand 785 192 $947,677
Praluent Pen (Alirocumab) Brand 569 95 $429,075
Clopidogrel (Clopidogrel Bisulfate) Brand 549 159 $9,613
Furosemide Generic 343 120 $2,450

Frequently asked questions

Auto-generated from federal data
What is Dr. John Isaac's medical specialty?
Dr. John Isaac practices Interventional Cardiology Physician in Houston, TX.
Where does Dr. John Isaac practice?
Dr. John Isaac practices at 6560 Fannin St, Houston, TX 770302761. Office phone: 7137911978.
What is Dr. John Isaac's NPI?
Dr. John Isaac's National Provider Identifier (NPI) is 1295799005, issued by NPPES.
Does Dr. John Isaac accept Medicare assignment?
Yes. Dr. John Isaac accepts Medicare assignment, meaning Medicare-allowed amounts are accepted as full payment for covered services.
What procedures does Dr. John Isaac commonly perform?
Top Medicare-reported procedures in 2023: Established patient office or other outpatient visit (HCPCS 99214); Injection, regadenoson, 0.1 mg (HCPCS J2785); Ultrasound of heart with color-depicted blood flow, rate, direction and valve function (HCPCS 93306). Source: CMS Medicare Physician & Other Practitioners file.