Doctor profile · Federal record

Dr. Manuel Santiago, MD

Hematology & Oncology Physician (CMS: Hematology/Oncology) · San Antonio, TX

  • NPI 1760454458
  • Accepts Medicare
  • MIPS 86.7 / 100 · 2023
  • 40 yrs in practice
  • Male
  • Group practice
  • No sanctions

Practice & contact

NPPES Updated May 11, 2026
Primary practice
5206 Research Dr
San Antonio, TX 782405251
(210) 595-5300
fax (210) 614-8740
Mailing address
Po Box 911230
Dallas, TX 753911230

Credentials & registration

NPPES · NUCC
NPI registered
February 2006 — 20 yrs on file
Profile last updated
February 26, 2018
Year of graduation
1986 — 40 yrs since
Specialty taxonomy
207RH0003X — NUCC code
State license (1)
Texas #J7651
Medicaid (3)
TX #126541501 · TX #126541506 · TX #126541507

Federal sanctions & exclusions

OIG LEIE Updated May 11, 2026

No sanctions, exclusions or revocations on file

Checked against OIG LEIE on NPI 1760454458. Last verified May 11, 2026.

Medicare procedures · 2023

Top services delivered

CMS Provider Utilization
Total services
44,847
Distinct HCPCS
10
Medicare allowed
$230,618
HCPCS Description Services Patients Avg allowed
Q0138 Injection, ferumoxytol, for treatment of iron deficiency anemia, 1 mg (non-esrd use) 15,810 25 $0
J9025 Injection, azacitidine, 1 mg 9,700 13 $0
J0881 Injection, darbepoetin alfa, 1 microgram (non-esrd use) 6,350 14 $3
Q9967 Low osmolar contrast material, 300-399 mg/ml iodine concentration, per ml 4,762 51 $0
J9041 Injection, bortezomib, 0.1 mg 1,330 14 $5
36415 Insertion of needle into vein for collection of blood sample 702 251 $8
80053 Blood test, comprehensive group of blood chemicals 684 256 $10
85025 Complete blood cell count (red cells, white blood cell, platelets), automated test and automated differential white blood cell count 675 254 $8
99214 Established patient office or other outpatient visit, 30-39 minutes 495 197 $120
J1626 Injection, granisetron hydrochloride, 100 mcg 440 22 $0

In context: peer comparison

Among 22 peers in this city , average services per provider: 1,021. This provider delivers 44× the peer median.

Open Payments

Industry payments received

CMS Open Payments
All-time total
$147
Transactions
3
Manufacturers
3
Payer (manufacturer) Industry Txns Amount
E.R. Squibb & Sons, L.L.C. 1 $102.32
Alexion Pharmaceuticals, Inc. 1 $30.00
Gilead Sciences, Inc. 1 $14.94

By nature of payment

Food and Beverage
$117
Education
$30

Medicare Part D · 2023

Top prescriptions

CMS Part D Prescriber
Total claims
603
Patients
89
Total drug cost
$1,580,721
Drug Type Claims Patients Total cost
Anastrozole Generic 74 19 $1,711
Eliquis (Apixaban) Brand 74 16 $60,121
Xarelto (Rivaroxaban) Brand 56 12 $50,884
Revlimid (Lenalidomide) Brand 48 0 $659,965
Hydrocodone-Acetaminophen (Hydrocodone/Acetaminophen) Brand 45 17 $1,002
Warfarin Sodium Generic 45 12 $812
Letrozole Generic 43 13 $2,047
Jantoven (Warfarin Sodium) Brand 34 0 $382
Dexamethasone Generic 33 0 $694
Imbruvica (Ibrutinib) Brand 32 0 $535,984

Hospital affiliations

CMS Hospital Compare

Frequently asked questions

Auto-generated from federal data
What is Dr. Manuel Santiago's medical specialty?
Dr. Manuel Santiago practices Hematology & Oncology Physician in San Antonio, TX.
Where does Dr. Manuel Santiago practice?
Dr. Manuel Santiago practices at 5206 Research Dr, San Antonio, TX 782405251. Office phone: 2105955300.
What is Dr. Manuel Santiago's NPI?
Dr. Manuel Santiago's National Provider Identifier (NPI) is 1760454458, issued by NPPES.
Does Dr. Manuel Santiago accept Medicare assignment?
Yes. Dr. Manuel Santiago accepts Medicare assignment, meaning Medicare-allowed amounts are accepted as full payment for covered services.
What procedures does Dr. Manuel Santiago commonly perform?
Top Medicare-reported procedures in 2023: Injection, ferumoxytol, for treatment of iron deficiency anemia, 1 mg (non-esrd use) (HCPCS Q0138); Injection, azacitidine, 1 mg (HCPCS J9025); Injection, darbepoetin alfa, 1 microgram (non-esrd use) (HCPCS J0881). Source: CMS Medicare Physician & Other Practitioners file.